Locus-specific and activity-independent gene repositioning during early tumorigenesis
نویسندگان
چکیده
منابع مشابه
Locus-specific and activity-independent gene repositioning during early tumorigenesis
The mammalian genome is highly organized within the cell nucleus. The nuclear position of many genes and genomic regions changes during physiological processes such as proliferation, differentiation, and disease. It is unclear whether disease-associated positioning changes occur specifically or are part of more global genome reorganization events. Here, we have analyzed the spatial position of ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2008
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.200708204